楊浩康 Dr Yeung Ho Hong
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Influenza (the flu) virus infections - Explained by Dr. Yeung Ho Hong(楊浩康)

Dr. Yeung Ho Hong(楊浩康) explains Influenza (the flu) virus infections

Antiviral agents for influenza are medications used to treat or prevent influenza (the flu) virus infections. Here are the main categories and examples:

1. Neuraminidase Inhibitors
These drugs inhibit the neuraminidase enzyme, which is essential for the virus's replication and spread.

  • *Oseltamivir (Tamiflu)*: Administered orally, effective for treating and preventing influenza.
  • *Zanamivir (Relenza)*: Administered via inhalation, used for treatment and prevention.
  • *Peramivir (Rapivab)*: A single intravenous dose for treatment in severe cases.

2. Polymerase Inhibitors
These agents inhibit viral RNA polymerase, affecting viral replication.

  • *Baloxavir marboxil (Xofluza)*: A newer medication given as a single dose, effective against influenza A and B.

3. Adamantanes
These are older antiviral drugs that target the M2 protein of the virus.

  • *Amantadine* and *Rimantadine*: Primarily effective against influenza A; however, many strains have developed resistance, so they are less commonly used.

Usage Guidelines

  • *Timing*: Antivirals are most effective when started within 48 hours of symptom onset.
  • *Prophylaxis*: Can be used in individuals at high risk of complications or during outbreaks.

Side Effects

  • Common side effects include nausea and vomiting, especially with oseltamivir.
  • Zanamivir may cause respiratory issues in individuals with asthma or chronic obstructive pulmonary disease (COPD).

Recommendations

  • Vaccination remains the primary method of prevention against influenza.
  • Antivirals are a supplemental measure, particularly for high-risk populations or during severe outbreaks.

If you have specific questions about a particular antiviral or its use, Your doctor will help you solve your problem!

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